Gene therapy (in longevity context)
DEGentherapie (im Longevity-Kontext)
Gene therapy delivers genetic material to add, silence, or edit your genes. It usually uses AAV viral vectors for stable, long-term gene expression. Or it uses lipid nanoparticles for temporary delivery (like mRNA or gene-editing components). In longevity, the popular targets include telomerase (TERT), follistatin, Klotho, and partial reprogramming via OSK. OSK is three Yamanaka factors: Oct4, Sox2, and Klf4. (They leave out c-Myc to lower cancer risk.) The rodent data are strong for some of these. But human use is still pre-clinical. Some runs as small offshore or pay-to-play programs outside FDA oversight (like BioViva and Libella). The risks are real: immune reactions, cancer, and off-target edits. No anti-aging gene therapy is approved.
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