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Journal Articlenpj aging·Apr 2026

Cholesterol, Immune Cells, and IGF-1 Emerge as Key Longevity Signals

Key Insight

This study suggests cholesterol, immune health, and IGF-1 may be worth monitoring as part of a longevity-focused check-up.


Researchers combed through massive genetic databases to find what actually drives long life and slower biological aging. Three factors stood out: cholesterol levels, immune cell traits, and IGF-1 (a growth hormone linked to aging). They also flagged 30 genes and several proteins as possible drug targets for future anti-aging therapies.

Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.