Autonomic nervous system
DEAutonomes Nervensystem
Reviewed by Maurice Lichtenberg
The autonomic nervous system (ANS) regulates involuntary bodily functions including heart rate, blood pressure, digestion, and respiration. It is traditionally divided into sympathetic (fight-or-flight) and parasympathetic (rest-and-digest) divisions, with the enteric nervous system commonly recognized as a semi-autonomous third division regulating the gastrointestinal tract. In longevity science, ANS function is assessed via HRV, baroreflex sensitivity, and heart rate recovery, since dysautonomia and chronic sympathetic dominance are implicated in cardiovascular disease and accelerated biological aging.
Sources
- Malik M, Bigger JT, Camm AJ, et al.. (1996). Heart rate variability: Standards of measurement, physiological interpretation, and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. *European Heart Journal*doi:10.1093/oxfordjournals.eurheartj.a014868
- Errico JP, Ben-Azu B, Gargus M, et al.. (2025). Sympathetic-parasympathetic system deregulation theory of aging. *npj Aging*doi:10.1038/s41514-025-00293-2
